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In initiating treatment for type 2 diabetesdiet should be emphasized as the primary form of treatmentCaloric restriction and weight loss are essential in the obese diabetic patientProper dietary management alone may be effective in controlling the blood glucose and symptoms of hyperglycemiaThe importance of regular physical activity should also be stressedand cardiovascular risk factors should be identified and corrective measures taken where possibleUse of MICRONASE or other antidiabetic medications must be viewed by both the physician and patient as a treatment in addition to diet and not as a substitution or as a convenient mechanism for avoiding dietary restraintFurthermoreloss of blood glucose control on diet alone may be transientthus requiring only short-term administration of MICRONASE or other antidiabetic medicationsMaintenance or discontinuation of MICRONASE or other antidiabetic medications should be based on clinical judgment using regular clinical and laboratory evaluations.

A diabetic dietor diabetes diet helps keep blood glucose levels in the target range for patientsExercise and medication may also help stabilize blood glucose levelsKeeping track of when you take your diabetic medicinekeeping track of food choiceseating the proper amount of fruitsvegetablescarbohydratesand fats will also help maintain proper blood glucose levelsFoods that raise blood sugar levels arehigh glycemic index foodsexamples include:

Glyburide appears to lower the blood glucose acutely by stimulating the release of insulin from the pancreasan effect dependent upon functioning beta cells in the pancreatic isletsThe mechanism by which glyburide lowers blood glucose during long-term administration has not been clearly establishedWith chronic administration in Type II diabetic patientsthe blood glucose lowering effect persists despite a gradual decline in the insulin secretory response to the drugExtrapancreatic effects may be involved in the mechanism of action of oral sulfonylurea hypoglycemic drugsThe combination of glyburide and metformin may have a synergistic effectsince both agents act to improve glucose tolerance by different but complementary mechanisms.

Stop taking this medication and call your doctor at once if you have any of these serious side effects:

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