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Prescribing Keflex in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Methicillin-resistant staphylococci and most isolates of enterococci are resistant to cephalexinCephalexin is not active against most isolates of Enterobacter sppMorganella morganiiand Proteus vulgarisCephalexin has no activity against Pseudomonas sppor Acinetobacter calcoaceticusPenicillin-resistant Streptococcus pneumoniae is usually cross-resistant to beta-lactam antibacterial drugs.

Liver functionCephalexin can cause a decrease in liver functionalthough this happens only occasionallyPeople with liver disease or reduced liver function should discuss with their doctor how this medication may affect their medical conditionhow their medical condition may affect the dosing and effectiveness of this medicationand whether any special monitoring is neededIf you experience signs of decreasing liver functionsuch as yellowing of the skin or whites of the eyesdark urineor pale stoolscontact your doctor as soon as possible.

If an allergic reaction to KEFLEX occursdiscontinue the drug and institute appropriate treatment.

In addition to the adverse reactions listed above that have been observed in patients treated with KEFLEXthe following adverse reactions and other altered laboratory tests have been reported for cephalosporin class antibacterial drugs:

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