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Triple TherapyNEXIUM plus amoxicillin and clarithromycinNEXIUMin combination with amoxicillin and clarithromycinis indicated for the treatment of patients with Hpylori infection and duodenal ulcer diseaseactive or history of within the past 5 yearsto eradicate HpyloriEradication of Hpylori has been shown to reduce the risk of duodenal ulcer recurrencesee DOSAGE AND ADMINISTRATION and Clinical Studies

Published observational studies suggest that PPI therapy like NEXIUM may be associated with an increased risk of Clostridium difficile associated diarrheaespecially in hospitalized patientsThis diagnosis should be considered for diarrhea that does not improvesee ADVERSE REACTIONS

Hypersensitivity Reactionssee CONTRAINDICATIONSAcute Interstitial Nephritissee WARNINGS AND PRECAUTIONSClostridium difficile Associated Diarrheasee WARNINGS AND PRECAUTIONSBone Fracturesee WARNINGS AND PRECAUTIONSCutaneous and Systemic Lupus Erythematosussee WARNINGS AND PRECAUTIONSCyanocobalaminVitamin B-12Deficiencysee WARNINGS AND PRECAUTIONSHypomagnesemiasee WARNINGS AND PRECAUTIONSDrug Interactions Advise patients to let you know if they are takingor begin takingother medicationsbecause NEXIUM can interfere with antiretroviral drugs and drugs that are affected by gastric pH changessee DRUG INTERACTIONS

The following serious adverse reactions are described below and elsewhere in labeling:

Nexium is used to treat symptoms of gastroesophageal reflux diseaseGERDand other conditions involving excessive stomach acid such as Zollinger-Ellison syndromeIt is also used to promote healing of erosive esophagitisdamage to your esophagus caused by stomach acid

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i ve been on nexium for 12 years and it doesn t completely do away with the heartburn, so it s going to be a big problem trying something else.