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EVISTA should not be used for the primary or secondary prevention of cardiovascular diseaseIn a clinical trial of postmenopausal women with documented coronary heart disease or at increased risk for coronary eventsno cardiovascular benefit was demonstrated after treatment with raloxifene for 5 yearssee Clinical Studies

Uterine fibroids are benignnon-canceroustumors in the wombuterusMost uterine fibroids do not cause symptomshoweverif the fibroid is large enough and in the right locationit may cause symptoms of pelvic painabnormal vaginal bleedingand pressure on the bladder or rectum.

After an assessment of the risk of developing breast cancerthe decision regarding therapy with EVISTA should be based upon an individual assessment of the benefits and risksEVISTA does not eliminate the risk of breast cancerPatients should have breast exams and mammograms before starting EVISTA and should continue regular breast exams and mammograms in keeping with good medical practice after beginning treatment with EVISTA.

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