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Decrease of hypoglycemic effect of glucophage is caused by co-administration with thyroid medicines, birth control pills and other hormones, epinephrine, glucagon, thiazide diuretics, nicotinic acid derivates.
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Minor side effects usually go away after your body gets used to taking the medicine for several weeksand may include mild diarrheanauseaor upset stomach.
Should generally be avoided in patients with clinical or laboratory evidence of hepatic diseasepatients should be cautioned against excessive alcohol intakeeither acute or chronicduring metformin therapy because alcohol potentiates the effects of metformin on lactate metabolism.
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