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Figure 2Mean Change in Total Symptom Score from Baseline Long-termOpen-labelNon-placebo Controlled StudyN494)
Orally administered Hytrin is indicated in adults for the treatment of mild to moderate hypertensionIt may be used in combination with thiazide diuretics and/or other antihypertensive drugs or as sole therapy where other agents are inappropriate or ineffectiveThe hypotensive effect is most pronounced on the diastolic pressureAlthough the exact mechanism of the hypotensive action of terazosin is not establishedthe relaxation of peripheral blood vessels appears to be produced mainly by competitive antagonism of post-synaptic alpha-1-adrenoceptorsHytrin usually produces an initial gradual decrease in blood pressure followed by a sustained antihypertensive action.
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