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Know the medicines you takeKeep a list of your medicines with you to show your healthcare providers when you get a new medicine.

LHRH is given as an injection or a tiny implant injected through a needle under the skin around your navelLHRH injections are given at intervals such as once every 4 weeksFollow your doctor’s instructions.

Hepatic side effects including severe liver injury leading to hospitalization and death have been reported rarelyHepatitis or marked increases in liver enzymes leading to drug discontinuation have been reported in approximately 1of bicalutamide patientsOne case of fulminant hepatic failure associated with bicalutamide use has also been reportedRef]

The safety and effectiveness of Casodex in pediatric patients have not been established.

Quality of life was assessed with self-administered patient questionnaires on painsocial functioningemotional well-beingvitalityactivity limitationbed disabilityoverall healthphysical capacitygeneral symptomsand treatment related symptomsAssessment of the Quality of Life questionnaires did not indicate consistent significant differences between the two treatment groups.

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