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Obesity is one of the most common health concerns todayHerbal-based food supplements are widely used to treat obesityAmong themthe African cactiform Hoodia gordonii supplements are extremely popularThe development of Hoodia and P57the purported active ingredienthas been problematic due to controversy about intellectual property rights and limited natural resourcesTo datethe true active components and molecular targets of Hoodia remain unclearHerewe demonstrate that Gordonoside Fa compound from Hoodiaactivates GPR119a receptor critically involved in metabolic homeostasisand leads to increased insulin secretion and reduced food intakeThe successful synthesis of Gordonoside F described here will provide an opportunity for developing new drugs in treating metabolic diseases.

Be careful when buying hoodia productsAccording to news reportssome samples of hoodia sold on the Internet do not contain any hoodia at allYou might not get what’s listed on the label.

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To reassure consumers of the efficacy of Hoodoba diet pillsthe Hoodoba site goes on to quote the likely imaginary ProfPIvanov of the likely imaginary NewLife Health InstituteIf Ivanov existshe hasn’t published any papers in the last 57 years.

Molecular matchmaking between the popular weight-loss herb Hoodia gordonii and GPR119a potential drug target for metabolic disorder.

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