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Following vaccination during an influenza a outbreak, symmetrel amantadine hydrochloride prophylaxis should be considered for the 2- to 4-week time period required to develop an antibody response.
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An antivial that is usd in th pophylactic symptomatic tatmnt inlunza A. It is alsusd as an antipakinsonian agnt, ttat xtapyamidal actions, and posthptic nualgia. Th mchanisms its cts in movmnt disods a not wll undstood but pobably lct an incas in synthsis and las dopamin, with phaps som inhibition dopamin uptak. [PubChm]
In addition, this dug is usd tpvnt and tat inlunza A vius inction. Amantadin is not a substitut annual lu shots.
Taking amantadin with anticholingic mdications can incas sid cts both dugs, such as dy mouth, uinay tntion, blud vision, and dowsinss. xampls anticholingic dugs includ:
Th mchanism its antipakinsonic ct is not ully undstood, but it appas tb lasing dopamin om th nv ndings th bain clls, togth with stimulation nopinphin spons. It alshas NMDA cptantagonistic cts. Th antivial mchanism sms tb unlatd. Th dug ints with a vial potin, M2 (an ion channl), which is ndd th vial paticl tbcom “uncoatd” onc it is takn insid th cll by ndocytosis.
Nappciabl mtabolism, although ngligibl amounts an actyl mtabolit hav bn idntiid.
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